Dr. Jaeyoung Shin

PostDoc

 

I was born in Gyeonggi-do, Korea. I spent the school years in Seoul, where I received my MSc degree in Molecular biology. I discovered that activation of the Ras/Raf/MEK/Erk pathway causes an accumulation of B-Raf and in particular its active mutant form V600E in the myonuclei and that embryonic forelimb muscle development is controlled by B-Raf through regulation of muscle precursor cell migration.

In 2015, I joined Prof. Dr. Krishnaraj Rajalingam's Group as a Postdoctoral Fellow.

My current research interest is focused on the understanding of Phosphorylation-Ub crosstalk in regulating RAF kinases and other related members of the kinome in normal and patho-physiology.

 

 

 

EDUCATION

 

 

2015 - current   PostDoc, Molecular Signaling Unit (Prof. Dr. Krishnaraj                                                           Rajalingam), Institute for Immunology, Johannes Gutenberg University,                             Mainz, Germany

 

2012 - 2014       Max Planck Institute for Heart and Lung Research

                            Postdoctral research at Department of Cardiac Development and                                       Remodelling, Bad Nauheim, Germany

 

October 2013   PhD thesis defended, Giessen University, Doctor biologiae hominis,                                      Medicine

 

2007 - 2012      PhD. student at Department of Cardiac Development and Remodelling

                           Max Planck Institute for Heart and Lung Research, Bad Nauheim,                                        Germany

 

2004 - 2006      Dankook University, Master of Science, Molecular Biology & Institute of                              Nanosensor and Biotechnology, Korea

 

1997 - 2000      Korean Artillery Army

 

1996 - 2004      Dankook University, Bachelor of Science, Molecular Biology, Korea

 

 

 

 

PUBLICATIONS

 

 

• Jochen Pöling, Praveen Gajawada, Manfred Richter, Holger Lörchner, Viktoria Polyakova, Sawa Kostin, Jaeyoung Shin, Astrid Wietelmann, Thomas Böttger, Thomas Kubin and Thomas Braun. (2014) Therapeutic targeting of the oncostatin M receptor-β prevents inflammatory heart failure. Basic Res Cardiol, 109 (1):396

 

• Jochen Pöling, Marten Szibor, Silvia Schimanski, Marie Ingelmann, Praveen Gajawada, Zaber Kochfar, Holger Lörchner, Isabelle Salwig, Jaeyoung Shin, Thomas Kubin, Henning Warnecke und Thomas Braun. (2011) Induction of smooth muscle cell migration during arteriogenesis is mediated by Rap2. Arterioscler Thromb Vasc Biol, 31(10):2297-305

 

• Jaeyoung Shin, Hanjoong Jo, Heonyong Park. (2006) Caveolin-1 is transiently dephosphorylated by shear stress-activated protein tyrosine phosphatase mu. Biochemical and Biophysical Research Communications, 339:3, 737-741

 

• Jaeyoung Shin, Jongmin Kim, Byungkyu Ryu, Sung-Gil Chi and Heonyong Park. (2006) Caveolin-1 Is Associated with VCAM-1 Dependent Adhesion of Gastric Cancer Cells to Endothelial Cells. Cellular Physiology and Biochemistry, 17, 211-220

 

• Jaeyoung Shin, Minho Cho, June Won Hyun, Jaeho Pyee, Heonyong Park. (2006) A new method for immobilization of lipid-binding proteins to the glass slides. Current Applied Physics, 6:2, 271-274

 

• Heonyong Park, Jaeyoung Shin, Jung Weon Lee & Hanjoong Jo. (2004) Fibronectin‐dependent cell adhesion is required for shear‐dependent ERK activation. Korean Journal of Biological Sciences, 8:1, 27-32