Dr. Sebastian Rosigkeit

PostDoc

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Sebastian studied biology at the JGU in Mainz. He became interested in cancer research and did his diploma thesis at the Institute of Toxicology, where he generated and modified a lung cancer cell line to study the tumor microenvironment. In 2013, he started his PhD project at the Institute of Translational Oncology (TRON) as a scholar of the “Stiftung Rheinland-Pfalz für Innovation”. During his PhD, he established a novel genetically engineered mouse model for lung cancer research and worked on the combination of cancer immunotherapies. He continued his PhD at the Institute of Translational Immunology (TIM) and received his doctorate end of 2017. Since 2018, he joined Prof. Krishnaraj Rajalingam's Group as a Postdoctoral Fellow.

  

EDUCATION

  

2018               PostDoc in Prof. Rajalingams Group 

 

2013 - 2017   PhD student at the Institute of Translational Oncology and Institute of

                        Translational Immunology, University Medical Center of the JGU Mainz

 

2005 - 2012   Biology Diploma, Johannes Gutenberg University Mainz

 

PUBLICATIONS​

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• Foerster F, Boegel S, Heck R, Pickert G, Rüssel N, Rosigkeit S, Bros M, Strobl S, Kaps L, Aslam M, Diken M, Castle J, Sahin U, Tuettenberg A, Bockamp E, Schuppan D. Enhanced protection in C57BL/6 mice to melanoma liver metastasis is mediated by NK cells. OncoImmunology. 2017 Dec 26; doi: 1080/2162402X.2017.1409929.

 

• Luther J, Yorgan TA, Rolvien T, Ulsamer L, Koehne T, Liao N, Keller D, Vollersen N, Teufel S, Neven M, Peters S, Schweizer M, Trumpp A, Rosigkeit S, Bockamp E, Mundlos S, Kornak U, Oheim R, Amling M, Schinke T, David JP. Wnt1 is an Lrp5-independent bone-anabolic Wnt Ligand. Sci Transl Med. 2018 Nov 7;10(466).

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• Rosigkeit S, Meng M, Grunwitz C, Gomes P, Kreft A, Hayduk N, Heck R, Pickert G, Ziegler K, Abassi Y, Röder J, Kaps L, Vascotto F, Beissert T, Witzel S, Kuhn A, Diken M, Schuppan D, Sahin U, Haas H, Bockamp E. Monitoring Translation Activity of mRNA-Loaded Nanoparticles in Mice. Mol Pharm. 2018 Sep 4;15(9):3909-3919.

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• Kaps L, Nuhn L, Aslam M, Foerster F, Rosigkeit S, Renz P, Heck R, Kim YO, Lieberwirth I, Schuppan D, Zentel R. In vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles. Adv Healthc Mater. 2015 Dec 30. doi:10.1002/adhm.201500826.

 

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